Prominent Microscopic Effects in Microfluidic Biochemical Analysis Systems
Acknowledgements
Introduction
Physics of Microfluidics
Silicon Micromachining
Valveless Flow Switching
Flow switching between two channels.
Switching Time
Microfluid flow is low Reynolds number flow.
Diffusion becomes more prominent at small scales.
Diffusive flow in a microchannel.
How an H Filter works.
The volume/surface area problem
Protein Adsorption
PPT Slide
Diffusion based separation.
Brightfield view of device
Flow pattern at the intersection
Flow pattern at the intersection.
Small molecules diffusing.
Whole Blood (FITC albumin diffusing)
Quantitative diffusion measurements
Conclusions
Email: jpbrody@u.washington.edu
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